vendredi 28 mars 2014

More on autism, key alterations are in the brain wiring

http://www.nejm.org/doi/full/10.1056/NEJMoa1307491?

"In conclusion, we identified discrete patches of disorganized cortex in the majority of postmortem samples obtained from young autistic children that we examined. These patches occurred in regions mediating the functions that are disturbed in autism: social, emotional, communication, and language functions. Such abnormalities may represent a common set of developmental neuropathological features that underlie autism and probably result from dysregulation of layer formation and layer-specific neuronal differentiation at prenatal developmental stages."


http://www.medpagetoday.com/Neurology/Autism/44953?

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