https://insights.ovid.com/pubmed?pmid=28538501
http://www.ijidonline.com/article/S1201-9712(09)00145-3/fulltext
Table 1
Common pathogens associated with infection in sickle cell anemia with underlying mechanisms for predisposition
| Encapsulated bacteria (e.g., Streptococcus pneumoniae, Haemophilus influenzae, Neisseria meningitidis, Salmonella spp) | Impaired splenic function |
| Impaired opsonization | |
| Salmonellae | Recurrent vaso-occlusion with intestinal infarct, necrosis and increased gut permeability |
| Decreased neutrophil killing | |
| Malaria | Decreased deoxyhemoglobin solubility |
| Parvovirus | Increased red cell turnover |
| Hepatitis B, C | Multiple blood transfusion |
| Chlamydophila | Unknown |
| Yersinia enterocolitica | Iron overload |
| Mycoplasma | Unknown |
| Edwardsiella tarda | Increased intestinal permeability and biliary sludging |
And also Hypo or asplenism patients
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