dimanche 1 juillet 2018

Hormesis and low dose radiation

https://link.springer.com/book/10.1007%2F978-3-319-56372-5



"People in Ramsar, a city which lies on the coast of the Caspian Sea, receive annual doses as large as 260 mSv (13 times higher than the annual dose limit currently suggested for radiation workers by ICRP). Moreover, the indoor radon (222Rn) level in these areas reaches levels up to 31,000 Bq/m3 (more than 200 times higher than the action level suggested for radon by US EPA). In this study, all subjects were residents of Ramak, located in the high natural background radiation areas (HNBRAs) and Sadat Mahaleh (a nearby area with normal levels of background radiation) districts of Ramsar, Iran diagnosed with breast cancer (BC) (Stages I,II and III) aged 10-90 year. All of these patients were registered from March 21, 2004 till February 20, 2014, in the Razi hospital, Rasht, Iran and had breast-conserving surgery. Patients who had a mastectomy, Immunotherapy or chemotherapy treatment were excluded from the study. Factors such as ethnicity, diet, social and economic status were almost the same in these nonsmoker individuals. Dosimetry was carried out inside the patients’ houses both in HBRAs and NBRAs. Furthermore, indoor radon levels were measured by using CR‐39 dosimeters. Based on our inclusion and exclusion criteria, a total of 91 patients participated in this study (37 patients (40.7%) from HBRAs and 54 patients (59.3%) from nearby NBRAs. All BC patients were female and the mean ages of patients in HBRAs and NBRAs were 60.91±15.32 years (ranged 14- 84) and 55.37±20.11 years (ranged 16-90), respectively. Most of these BC patients were in stage II. The mean gamma dose rate for BC patients who lived in HNBR area (0.09±0.07 μSv h-1) was significantly higher (P<0 .0001="" 0.006="" 108.3="" 10="" 61.2="" 7.5="" 8.6="" a="" and="" area="" average="" bc="" bq="" br="" compared="" concentration="" data="" difference="" dysphagia="" erythema="" for="" from="" furthermore="" group.="" group="" groups="" h-1="" hbra="" hbras="" higher="" hnbr="" however="" in="" incidence="" kaplan-meier="" less="" lived="" m-3="" mean="" months="" moreover="" nalysis="" nbras="" nearby="" no="" observed="" of="" participated="" patients="" radiotherapy="" radon="" rate="" rates="" showed="" significant="" significantly="" statistically="" study="" survival="" test="" than="" that="" the="" there="" to="" two="" using="" v="" was="" were="" when="" who="" year="">



https://www.researchgate.net/publication/325180437_Breast_Cancer_Patients_who_Lived_in_Areas_with_Elevated_Levels_of_Natural_Background_Radiation_Show_Decreased_Erythema_Incidence_and_Higher_10_year_Survival_rate_after_Radiotherapy


https://www.em-consulte.com/article/1312686/pdf/faibles-doses-de-rayonnements%C2%A0-quand-l-hormesis-et

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