Circulating tumour cells present genomic alterations which could be exploited as targets

Whole genomic copy number alterations in circulating tumor cells from men with abiraterone or enzalutamide resistant metastatic castration-resistant prostate cancer: separation of those cells and then a complex genomic analysis, comparison  with white blood cells and identification of targets.
http://clincancerres.aacrjournals.org/content/early/2016/09/03/1078-0432.CCR-16-1211