mercredi 24 août 2016

Depression: news for intractable ones

Inline images 1
a Folinic acid (5-formyl-THF) enters the pathway without the action of DHFR and contributes active metabolites. 5-Methyl-THF is a distal metabolite. DHFR=dihydrofolate reductase; DHF=dihydrofolate; dTMP=deoxy-thymidine phosphate; dUMP=deoxy-uridine phosphate; NAD=nicotinamide adenine dinucleotide; NADP=nicotinamide adenine dinucleotide phosphate; NADPH=nicotinamide adenine dinucleotide phosphate, reduced; THF=tetrahydrofolate.

Aucun commentaire: