jeudi 31 octobre 2019

Out of Africa, a new scheme

Filiation and migration

10.1038/s41586-019-1714-1





Figure 2. Proposed evolutionary models for African genetic structure.
(a) Western Africa groups have ancestry from a basal western African lineage (WA1). The major source of western African ancestry (WA2) is more related to eastern Africans (EA) and non-Africans than Southern African Khoe-San (SA).
(b) West Africa populations have gene flow from a population related to both southern and eastern Africa, supporting a more complex pattern of isolation-by-distance (Redrawn from Skoglund et al. [25••]).

Adaptation



Figure 2A map of human local adaptations in central Africa. Blue circles indicate case examples of candidate local adaptations and corresponding positively-selected genes in western/central Africa. Violet circles indicate candidate cases of adaptive admixture, when adaptive variation was acquired through admixture or gene flow. The orange area shows where Bantu languages are spoken today (adapted from Ref. [3]). Dark green areas indicate the geographic areas that the different RHG groups occupy (adapted from Ref. [1]). The maroon hatched areas indicate predicted areas of high Plasmodium falciparum malaria endemicity [95].

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