CCR5, Gabor's theorem and He Jiankui

"The Chinese researcher He Jiankui at a genome editing conference on Wednesday. Dr He says he had modified the genes of twins who were born in November to protect them from H.I.V."
https://www.nytimes.com/2018/12/01/sunday-review/crispr-china-babies-gene-editing.html

The concert of convictions is typical of this kind of event. Two reflections: 1 / 99% of people who speak do not know anything about it. In order to better understand the issue, this paper will bring you a level of complexity about the CCR5 receptor (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185609/), and this one about HIV infectivity (https://academic.oup.com/ve/article/4/2/vey032/5196405) 2 / I recall Dennis Gabor's theorem: "all that scientists can do they will do it". Then everyone will choose. We have hybridized animals, plants and our sexual dimorphism is not a random match. It is therefore inevitable that we try to increase the human genetic potential. As for any therapeutic, because it is preventive therapeutic in this case, it will be necessary to prove that the ratio B / R is positive and to measure it. And as for all improvement, the need for a disruption is obvious even in the meaning of some men and women freely deciding to embark on a new treatment because of a dangerous disease.

In front of those Pavlovian negative judgements from institutions the excellent piece of Eric J. Topol:
https://www.nytimes.com/2018/12/01/sunday-review/crispr-china-babies-gene-editing.html






Le concert de convictions est typique de ce genre d’événement. Deux réflexions:  1/99% des personnes qui parlent ne savent rien à ce sujet. Afin de mieux comprendre la question, ce document vous apportera un niveau de complexité supplémentaire concernant le récepteur CCR5 (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185609/), et celui-ci sur l'infectivité du VIH. (https://academic.oup.com/ve/article/4/2/vey032/5196405)  2 / Je me souviens du théorème de Dennis Gabor: "tout ce que les scientifiques peuvent faire, ils le feront". Ensuite, tout le monde choisira. Nous avons hybridé des animaux, des plantes et notre dimorphisme sexuel ne correspond pas à un appariement aléatoire. Il est donc inévitable d'essayer d'accroître le potentiel génétique humain. Comme pour toute thérapeutique, puisqu'il s'agit d'une thérapie préventive dans ce cas, il faudra prouver que le rapport B / R est positif et le mesurer. Et comme pour toute amélioration, la nécessité d'une perturbation est évidente, même dans le sens où certains hommes et femmes décident librement de se lancer dans un nouveau traitement en raison d'une maladie dangereuse.


https://livestream.com/NASEM/events/8464254/videos/184208331

https://livestream.com/NASEM/events/8464254/videos/184103056