dimanche 9 juillet 2017

Is pneumococcal vaccine for every child?


https://insights.ovid.com/pubmed?pmid=28538501

http://www.ijidonline.com/article/S1201-9712(09)00145-3/fulltext

Table 1 

Common pathogens associated with infection in sickle cell anemia with underlying mechanisms for predisposition

Table 1 Common pathogens associated with infection in sickle cell anemia with underlying mechanisms for predisposition
PathogenPredisposing factors
Encapsulated bacteria (e.g., Streptococcus pneumoniae, Haemophilus influenzae, Neisseria meningitidis, Salmonella spp)Impaired splenic function
Impaired opsonization
SalmonellaeRecurrent vaso-occlusion with intestinal infarct, necrosis and increased gut permeability
Decreased neutrophil killing
MalariaDecreased deoxyhemoglobin solubility
ParvovirusIncreased red cell turnover
Hepatitis B, CMultiple blood transfusion
ChlamydophilaUnknown
Yersinia enterocoliticaIron overload
MycoplasmaUnknown
Edwardsiella tardaIncreased intestinal permeability and biliary sludging

And also Hypo or asplenism patients

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