samedi 10 octobre 2015

Statistiques de mortalité en France.

http://m.leparisien.fr/societe/les-canicules-de-l-ete-2015-ont-provoque-3300-deces-supplementaires-09-10-2015-5171099.php

Ce rapport n'est vraiment pas très sérieux. Il souligne encore l'incapacité de l'administration française à obtenir des données statistiques. Il faut urgemment rémunérer les certificats de décès de telle sorte qu'il soit remplie de manière la plus exhaustive possible.\Cela bien sûr ne peut se faire avec la bureaucratie actuelle est la paperasse qui nous est imposé. Il faut passer à une déclaration électronique beaucoup plus détaillé qui permet d'entrer des mots-clés spécifiant l'état réel de la personne décédée.

Peter's principle

PETER PRINCIPLE (With Ben Carson brain surgeons are finally rising to the level of  their incompetence)

"Great distinction in one field is no protection against unmitigated foolishness in another. Bobby Fischer may have been the greatest chess genius ever, but he ended up a paranoid anti-Semite.  Carson is an exceptional surgeon who knows very little about public policy or history and has a habit of letting his imagination fill in the gaps."

https://reason.com/archives/2015/10/08/ben-carson-and-the-politics-of-fantasy

"In time, every post tends to be occupied by an employee who is incompetent to carry out its duties. Do not be fooled by apparent exceptions." 

"Work is accomplished by those employees who have not yet reached their level of incompetence."

Laurence J. Peter 

https://en.wikipedia.org/wiki/Peter_principle

If a cluttered desk is a sign of a cluttered mind, of what, then, is an empty desk a sign?

When you see yourself quoted in print and you're sorry you said it, it suddenly becomes a misquotation.

Some problems are so complex that you have to be highly intelligent and well informed just to be undecided about them.

Laurence J. Peter 

https://en.wikiquote.org/wiki/Laurence_J._Peter

"I have seen people on school boards that were good, Christian people. That got elected because they were good, Christian people. They went on school boards and ended up with grand juries coming after them not because they were bad people but because they were so over their heads on the Escambia County school board, And people are looking at this guy and saying he’s a good, decent, Christian guy and they are ready for him to be President of the United States. I am sorry, I’m going to stop right here. And I’m not going to get on this train where I say I understand why people would vote for Ben Carson as president of the United States. And I can tell you, we’re going down a dangerous path as a party and a dangerous path as a country if we Republicans or Democrats start electing people because they’re nice Christian folk.”

“[I] know there are a couple of idiots that are going to say, ‘Oh, Manhattan elites and Joe Scarborough, da da da da.’ No, all of these people — I know them. They all voted for me. And quite frankly if I ran again they would vote for me again despite what I’m saying right now about Ben Carson. I’m not being an elitist when I say Ben Carson is not qualified to be president of the United States. I don’t get why they aren’t talking about someone who can actually get us out of the mess–I say this as a Republican–Barack Obama has put us.”

Joe Scarborough 

http://www.breitbart.com/video/2015/10/08/scarborough-im-not-being-an-elitist-when-i-say-ben-carson-is-not-qualified-to-be-president/

jeudi 8 octobre 2015

Antibiotic consumption in France: geographic variations are not appropriate

Affichage de image.png en cours...
Des  disparités de consommation évidentes et inappropriées

Fluoroquinolones: do you actually need them?

http://archinte.jamanetwork.com/article.aspx?articleid=2451282
http://archinte.jamanetwork.com/article.aspx?articleid=2451282

The common thread between Achille's tendon rupture and aortic aneurisms or dissection is Collagen.
Fluoroquinolones alter collagen.

"La France n’a pas pour l’instant mis en place un tel niveau d'alerte, les tendinites sont simplement mentionnées dans les sections « mises en garde » des notices. Cela crée une importante incohérence entre les avertissements données aux consommateurs européens et ceux dont bénéficient les consommateurs nord-américains. Les données de pharmacovigilance disponibles indiquent pourtant un risque accru de tendinopathies pour le consommateur français, qui pourrait être lié à l'utilisation plus grande en France de produits glucocorticoïdes amplifiant les effets indésirables tendineux des fluoroquinolones. Cette différence sur les notices des fluoroquinolones a connu un précédent notable et toujours d'actualité: bien que les risques d'atteintes séquellaires du système nerveux périphérique soient obligatoires depuis 2004 dans les notices américaines, ils sont absents des notices françaises."

A very disturbing study of Caen university by P Charbonneau

It means that probably the very strong diffusion of FQ in the skin frees an excellent econiche for SARM in inpatients.
At least 2/3 of FQ prescriptions are inappropriate.

https://academic.oup.com/cid/issue/42/6

https://www.bmj.com/content/360/bmj.k988/rapid-responses